Recurrence of cervical cancer and its resistance to progestin therapy in a mouse model.

Mehta, Fabiola F; Baik, Seunghan; Chung, Sang-Hyuk

Mehta, Fabiola F; Baik, Seunghan; Chung, Sang-Hyuk.

Affiliation

Mehta FF; Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
Baik S; Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
Chung SH; Center for Nuclear Receptors and Cell Signaling, Department of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.

Oncotarget ; 8(2): 2372-2380, 2017 Jan 10.

Article in En | MEDLINE | ID: mdl-27911853

Subject(s)

Antineoplastic Agents, Hormonal/therapeutic use; Drug Resistance, Neoplasm; Medroxyprogesterone Acetate/therapeutic use; Neoplasm Recurrence, Local; Uterine Cervical Neoplasms/drug therapy; Animals; Disease Models, Animal; Female; Male; Mice; Mice, Transgenic; Neoplasm Recurrence, Local/pathology; Neoplasm Recurrence, Local/prevention & control; Oncogene Proteins, Viral/genetics; Papillomavirus E7 Proteins/genetics; Repressor Proteins/genetics; Treatment Failure; Tumor Burden/drug effects; Uterine Cervical Neoplasms/genetics; Uterine Cervical Neoplasms/pathology

Key words

cervical cancer; human papillomavirus (HPV); medroxyprogesterone acetate (MPA); recurrence; therapy resistance

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uterine Cervical Neoplasms / Medroxyprogesterone Acetate / Drug Resistance, Neoplasm / Antineoplastic Agents, Hormonal / Neoplasm Recurrence, Local Type of study: Prognostic_studies Limits: Animals Language: En Journal: Oncotarget Year: 2017 Document type: Article Affiliation country: United States Country of publication: United States

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