Drug-drug cocrystals of antituberculous 4-aminosalicylic acid: Screening, crystal structures, thermochemical and solubility studies.

Drozd, Ksenia V; Manin, Alex N; Churakov, Andrei V; Perlovich, German L

Drozd, Ksenia V; Manin, Alex N; Churakov, Andrei V; Perlovich, German L.

Affiliation

Drozd KV; G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences, 1, Akademicheskaya St., 153045 Ivanovo, Russia.
Manin AN; G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences, 1, Akademicheskaya St., 153045 Ivanovo, Russia.
Churakov AV; Institute of General and Inorganic Chemistry, RAS, Leninsky Prosp. 31, 119991 Moscow, Russia.
Perlovich GL; G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences, 1, Akademicheskaya St., 153045 Ivanovo, Russia. Electronic address: glp@isc-ras.ru.

Eur J Pharm Sci ; 99: 228-239, 2017 Mar 01.

Article in En | MEDLINE | ID: mdl-28011126

Subject(s)

Aminosalicylic Acid/chemistry; Antitubercular Agents/chemistry; Caffeine/chemistry; Crystallization; Crystallography, X-Ray/methods; Drug Stability; Isoniazid/chemistry; Models, Molecular; Niacinamide/chemistry; Powder Diffraction/methods; Pyrazinamide/chemistry; Solubility; Theophylline/chemistry; X-Ray Diffraction/methods

Key words

4-Aminosalicylic acid (PubChem CID: 4649); Acetone (PubChem CID: 180); Acetonitrile (PubChem CID: 6342); Caffeine (PubChem CID: 2519); Cocrystal; Crystal structure; Desolvation; Dissolution rate; Ethanol (PubChem CID: 702); Isoniazid (PubChem CID: 3767); Isonicotinamide (PubChem CID: 15074); Melting points; Methanol (PubChem CID: 887); Nicotinamide (PubChem CID: 936); Pyrazinamide (PubChem CID: 1046); Screening; Tetrahydrofuran (PubChem CID: 8028); Theophylline (PubChem CID: 2153)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aminosalicylic Acid / Antitubercular Agents Type of study: Diagnostic_studies / Screening_studies Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2017 Document type: Article Affiliation country: RUSSIA Country of publication: Netherlands

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