Synthesis, Characterization and Comparison of Local Analgesic, Anti-Inflammatory, Anti-Ulcerogenic Activity of Copper and Zinc Complexes of Indomethacin.

Sukul, Abhijit; Poddar, Saikat Kumar; Haque, Sanjana; Saha, Sajal Kumar; Das, Sreedam Chandra; Al Mahmud, Zobaer; Abdur Rahman, S M

Sukul, Abhijit; Poddar, Saikat Kumar; Haque, Sanjana; Saha, Sajal Kumar; Das, Sreedam Chandra; Al Mahmud, Zobaer; Abdur Rahman, S M.

Affiliation

Sukul A; Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka-1000, Bangladesh, and Department of Pharmacy, Northern University Bangladesh, Dhaka-1205. Bangladesh.
Poddar SK; Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka- 1000, Dhaka. Bangladesh.
Haque S; Department of Pharmacy, Northern University Bangladesh, Dhaka- 1205. Bangladesh.
Saha SK; Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka- 1000, Dhaka. Bangladesh.
Das SC; Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka- 1000, Dhaka. Bangladesh.
Al Mahmud Z; Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka- 1000, Dhaka. Bangladesh.
Abdur Rahman SM; Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka- 1000, Dhaka. Bangladesh.

Antiinflamm Antiallergy Agents Med Chem ; 15(3): 221-233, 2017.

Article in En | MEDLINE | ID: mdl-28215165

Subject(s)

Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Coordination Complexes; Copper; Indomethacin; Zinc; Analgesics/adverse effects; Analgesics/chemistry; Analgesics/therapeutic use; Animals; Anti-Inflammatory Agents, Non-Steroidal/adverse effects; Anti-Inflammatory Agents, Non-Steroidal/chemistry; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use; Carrageenan; Coordination Complexes/adverse effects; Coordination Complexes/chemistry; Coordination Complexes/therapeutic use; Copper/chemistry; Copper/therapeutic use; Edema/chemically induced; Edema/drug therapy; Female; Hot Temperature; Indomethacin/adverse effects; Indomethacin/chemistry; Indomethacin/therapeutic use; Intestine, Small/drug effects; Intestine, Small/pathology; Male; Mice; Pain/drug therapy; Peptic Ulcer/chemically induced; Peptic Ulcer/pathology; Rats, Wistar; Stomach/drug effects; Stomach/pathology; Zinc/chemistry; Zinc/therapeutic use

Key words

Anti-inflammatory; anti-ulcerogenic activity; differential scanning calorimetry; indomethacin metal complexes; local analgesic; spectroscopy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Zinc / Anti-Inflammatory Agents, Non-Steroidal / Indomethacin / Copper / Coordination Complexes / Analgesics Language: En Journal: Antiinflamm Antiallergy Agents Med Chem Year: 2017 Document type: Article Country of publication: United Arab Emirates

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