Intermittent parathyroid hormone (PTH) promotes cementogenesis and alleviates the catabolic effects of mechanical strain in cementoblasts.

Li, Yuyu; Hu, Zhiai; Zhou, Chenchen; Xu, Yang; Huang, Li; Wang, Xin; Zou, Shujuan

Li, Yuyu; Hu, Zhiai; Zhou, Chenchen; Xu, Yang; Huang, Li; Wang, Xin; Zou, Shujuan.

Affiliation

Li Y; Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, No. 14, 3rd Section, Renmin South Road, Chengdu, 610041, China.
Hu Z; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, No. 14, 3rd Section, Renmin South Road, Chengdu, 610041, China.
Zhou C; Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, No. 14, 3rd Section, Renmin South Road, Chengdu, 610041, China.
Xu Y; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, No. 14, 3rd Section, Renmin South Road, Chengdu, 610041, China.
Huang L; Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, No. 14, 3rd Section, Renmin South Road, Chengdu, 610041, China.
Wang X; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, No. 14, 3rd Section, Renmin South Road, Chengdu, 610041, China.
Zou S; Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, No. 14, 3rd Section, Renmin South Road, Chengdu, 610041, China.

BMC Cell Biol ; 18(1): 19, 2017 04 20.

Article in En | MEDLINE | ID: mdl-28427342

Subject(s)

Cementogenesis/drug effects; Dental Cementum/cytology; Dental Cementum/drug effects; Parathyroid Hormone/pharmacology; Stress, Mechanical; Animals; Cell Differentiation/drug effects; Cell Line; Cementogenesis/genetics; Collagen Type I/genetics; Collagen Type I/metabolism; Dental Cementum/enzymology; Gene Expression Regulation/drug effects; Integrin-Binding Sialoprotein/genetics; Integrin-Binding Sialoprotein/metabolism; Mice; Osteocalcin/genetics; Osteocalcin/metabolism; Osteopontin/genetics; Osteopontin/metabolism; Parathyroid Hormone/administration & dosage; Receptor, Parathyroid Hormone, Type 1/genetics; Receptor, Parathyroid Hormone, Type 1/metabolism; Sp7 Transcription Factor/genetics; Sp7 Transcription Factor/metabolism; Time Factors; Tooth Root/cytology; Tooth Root/drug effects

Key words

Cementogenesis; Intermittent parathyroid hormone (PTH); Mechanical strain; OCCM-30 cell; Tooth root resorption

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parathyroid Hormone / Stress, Mechanical / Cementogenesis / Dental Cementum Limits: Animals Language: En Journal: BMC Cell Biol Year: 2017 Document type: Article Affiliation country: China Country of publication: United kingdom

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