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Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1.
Decker, Tim-Michael; Kluge, Michael; Krebs, Stefan; Shah, Nilay; Blum, Helmut; Friedel, Caroline C; Eick, Dirk.
Affiliation
  • Decker TM; Department of Molecular Epigenetics, Helmholtz Center Munich and Center for Integrated Protein Science Munich (CIPSM), Marchioninistrasse 25, 81377, Munich, Germany.
  • Kluge M; Institute for Informatics, Ludwig-Maximilians-Universität München, Amalienstr. 17, Munich, 80333, Germany.
  • Krebs S; Laboratory for Functional Genome Analysis (LAFUGA) at the Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Shah N; Department of Molecular Epigenetics, Helmholtz Center Munich and Center for Integrated Protein Science Munich (CIPSM), Marchioninistrasse 25, 81377, Munich, Germany.
  • Blum H; Laboratory for Functional Genome Analysis (LAFUGA) at the Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany.
  • Friedel CC; Institute for Informatics, Ludwig-Maximilians-Universität München, Amalienstr. 17, Munich, 80333, Germany.
  • Eick D; Department of Molecular Epigenetics, Helmholtz Center Munich and Center for Integrated Protein Science Munich (CIPSM), Marchioninistrasse 25, 81377, Munich, Germany. eick@helmholtz-muenchen.de.
Sci Rep ; 7(1): 1684, 2017 05 10.
Article in En | MEDLINE | ID: mdl-28490802
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azepines / Triazoles / Nuclear Proteins / Gene Expression Profiling / Small Molecule Libraries / Genes, Dominant / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: Germany Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azepines / Triazoles / Nuclear Proteins / Gene Expression Profiling / Small Molecule Libraries / Genes, Dominant / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: Germany Country of publication: United kingdom