The role of matrix metalloproteinases in aging: Tissue remodeling and beyond.

Freitas-Rodríguez, Sandra; Folgueras, Alicia R; López-Otín, Carlos

Freitas-Rodríguez, Sandra; Folgueras, Alicia R; López-Otín, Carlos.

Affiliation

Freitas-Rodríguez S; Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006 Oviedo, Spain.
Folgueras AR; Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006 Oviedo, Spain.
López-Otín C; Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006 Oviedo, Spain; Centro de Investigación Biomédica en Red de Cáncer, Spain. Electronic address: clo@uniovi.es.

Biochim Biophys Acta Mol Cell Res ; 1864(11 Pt A): 2015-2025, 2017 Nov.

Article in En | MEDLINE | ID: mdl-28499917

Subject(s)

Aging/metabolism; Extracellular Matrix/enzymology; Matrix Metalloproteinases/metabolism; Neurodegenerative Diseases/enzymology; Stem Cell Niche; Stem Cells/enzymology; Aging/pathology; Animals; Extracellular Matrix/pathology; Humans; Neurodegenerative Diseases/pathology; Stem Cells/pathology

Key words

Aging; Extracellular matrix; MMP; Protease; Senescence; Stem cell

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Aging / Neurodegenerative Diseases / Matrix Metalloproteinases / Extracellular Matrix / Stem Cell Niche Limits: Animals / Humans Language: En Journal: Biochim Biophys Acta Mol Cell Res Year: 2017 Document type: Article Affiliation country: Spain Country of publication: Netherlands

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