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Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulation.
Lan, Xiaoying; Zhao, Chong; Chen, Xin; Zhang, Peiquan; Zang, Dan; Wu, Jinjie; Chen, Jinghong; Long, Huidan; Yang, Li; Huang, Hongbiao; Wang, Xuejun; Shi, Xianping; Liu, Jinbao.
Affiliation
  • Lan X; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Zhao C; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Chen X; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Zhang P; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Zang D; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Wu J; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Chen J; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Long H; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Yang L; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Huang H; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Wang X; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
  • Shi X; Division of Basic Biomedical Sciences, Sanford School of Medicine of the University of South Dakota, Vermillion, SD 57069, USA.
  • Liu J; Protein Modification and Degradation Lab, SKLRD, School of Basic Medical Sciences, The affiliated Tumor Hospital of Guangzhou Medical University, Guangdong 511436, China.
Cell Death Dis ; 8(7): e2913, 2017 07 06.
Article in En | MEDLINE | ID: mdl-28682311
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organoplatinum Compounds / Pyridines / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Gene Expression Regulation, Leukemic / Fusion Proteins, bcr-abl / Caspases / Deubiquitinating Enzymes / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Cell Death Dis Year: 2017 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organoplatinum Compounds / Pyridines / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Gene Expression Regulation, Leukemic / Fusion Proteins, bcr-abl / Caspases / Deubiquitinating Enzymes / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Cell Death Dis Year: 2017 Document type: Article Affiliation country: China