Your browser doesn't support javascript.
loading
Changes in cardiac and muscle biomarkers following an uphill-only marathon.
Da Ponte, Alessandro; Giovanelli, Nicola; Antonutto, Guglielmo; Nigris, Daniele; Curcio, Francesco; Cortese, Pietro; Lazzer, Stefano.
Affiliation
  • Da Ponte A; a Department of Medicine , University of Udine , Udine , Italy.
  • Giovanelli N; b School of Sport Medicine , University of Udine , Udine , Italy.
  • Antonutto G; a Department of Medicine , University of Udine , Udine , Italy.
  • Nigris D; c School of Sport Sciences , University of Udine , Udine , Italy.
  • Curcio F; a Department of Medicine , University of Udine , Udine , Italy.
  • Cortese P; c School of Sport Sciences , University of Udine , Udine , Italy.
  • Lazzer S; a Department of Medicine , University of Udine , Udine , Italy.
Res Sports Med ; 26(1): 100-111, 2018.
Article in En | MEDLINE | ID: mdl-29058466
The aim of the study was to evaluate changes in cardiac troponin I levels (cTnI) and the main biomarkers of skeletal muscle damage after an uphill-only marathon, along with its relationship with athletes' physiological parameters. Twenty-two runners participated in the "Supermaratona dell'Etna" (43 km, 0-2850 m AMSL). Before and immediately after the race, body mass and hydration status were measured together with blood sampling. At the end of the race, mean cTnI increased significantly in all athletes (mean +900%), and in 52% of them the cTnI values were over the normal range. Mean creatinine and cortisol increased significantly (by 30.5% and 291.4%), while C-reactive protein levels did not change significantly. Then, an uphill-only marathon showed a significant increase in cardiac and skeletal muscle blood biomarkers of injury, and cTnI levels were not significantly correlated with age, body mass index, V̇O2max, training status, ultra-endurance training experience, race time and blood parameters.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Running / Biomarkers / Troponin I Limits: Adult / Humans / Male / Middle aged Language: En Journal: Res Sports Med Journal subject: MEDICINA ESPORTIVA Year: 2018 Document type: Article Affiliation country: Italy Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Running / Biomarkers / Troponin I Limits: Adult / Humans / Male / Middle aged Language: En Journal: Res Sports Med Journal subject: MEDICINA ESPORTIVA Year: 2018 Document type: Article Affiliation country: Italy Country of publication: United kingdom