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Sarcoidosis-lymphoma syndrome: a diagnostic dilemma.
Oskuei, Assad; Hicks, Lisa; Ghaffar, Hasan; Hoffstein, Victor.
Affiliation
  • Oskuei A; Department of Pulmonary and Critical Care, New York University School of Medicine, New York, USA.
  • Hicks L; Department of Internal Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Ghaffar H; Department of Pathology, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.
  • Hoffstein V; Department of Respirology, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.
BMJ Case Rep ; 20172017 Dec 14.
Article in En | MEDLINE | ID: mdl-29246929
Sarcoidosis and lymphoma are generally thought of as being two mutually exclusive diseases that need to be considered in the differential diagnosis of patients with hilar/mediastianal lymphadenopathy. However, there are rare patients in whom both of these diseases coexist. These patients constitute a diagnostic challenge because their presentation (ie, clinical symptoms, imaging abnormalities and even pathology) may all be atypical when each individual disease is considered separately. In this report, we describe a patient who presented with such atypical features and was eventually diagnosed as having both sarcoidosis and a B-cell lymphoma with features of splenic marginal zone lymphoma (SMZL) simultaneously. To our knowledge, this is only the second reported case of SMZL and sarcoidosis in the same patient.
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoidosis / Splenic Neoplasms / Lymphoma Type of study: Diagnostic_studies / Etiology_studies Limits: Adult / Female / Humans Language: En Journal: BMJ Case Rep Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoidosis / Splenic Neoplasms / Lymphoma Type of study: Diagnostic_studies / Etiology_studies Limits: Adult / Female / Humans Language: En Journal: BMJ Case Rep Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom