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Ryanodine-receptor inhibition by dantrolene effectively suppresses ventricular arrhythmias in an ex vivo model of long-QT syndrome.
Frommeyer, Gerrit; Krawczyk, Julius; Ellermann, Christian; Bögeholz, Nils; Kochhäuser, Simon; Dechering, Dirk G; Fehr, Michael; Eckardt, Lars.
Affiliation
  • Frommeyer G; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
  • Krawczyk J; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
  • Ellermann C; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
  • Bögeholz N; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
  • Kochhäuser S; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
  • Dechering DG; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
  • Fehr M; Clinic of Exotic Pets, Reptiles, Exotic and Feral Birds, University of Hanover, Hanover, Germany.
  • Eckardt L; Division of Electrophysiology, Department of Cardiovascular Medicine, University of Münster, Münster, Germany.
J Cardiovasc Electrophysiol ; 29(3): 471-476, 2018 03.
Article in En | MEDLINE | ID: mdl-29314443
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Long QT Syndrome / Calcium Channel Blockers / Torsades de Pointes / Ryanodine Receptor Calcium Release Channel / Dantrolene / Heart Rate / Heart Ventricles / Anti-Arrhythmia Agents Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Cardiovasc Electrophysiol Journal subject: ANGIOLOGIA / CARDIOLOGIA / FISIOLOGIA Year: 2018 Document type: Article Affiliation country: Germany Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Long QT Syndrome / Calcium Channel Blockers / Torsades de Pointes / Ryanodine Receptor Calcium Release Channel / Dantrolene / Heart Rate / Heart Ventricles / Anti-Arrhythmia Agents Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Cardiovasc Electrophysiol Journal subject: ANGIOLOGIA / CARDIOLOGIA / FISIOLOGIA Year: 2018 Document type: Article Affiliation country: Germany Country of publication: United States