Down-regulation of guanylate binding protein 1 causes mitochondrial dysfunction and cellular senescence in macrophages.

Qiu, Xiaoxue; Guo, Hong; Yang, Junshu; Ji, Yinduo; Wu, Chia-Shan; Chen, Xiaoli

Qiu, Xiaoxue; Guo, Hong; Yang, Junshu; Ji, Yinduo; Wu, Chia-Shan; Chen, Xiaoli.

Affiliation

Qiu X; Department of Food Science and Nutrition, College of Food, Agricultural and Natural Resource Sciences, University of Minnesota, Twin Cities, Minnesota, USA.
Guo H; Department of Food Science and Nutrition, College of Food, Agricultural and Natural Resource Sciences, University of Minnesota, Twin Cities, Minnesota, USA.
Yang J; Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Twin Cities, Minnesota, USA.
Ji Y; Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, Twin Cities, Minnesota, USA.
Wu CS; Department of Nutrition and Food Science, Texas A&M University, College Station, TX, USA.
Chen X; Department of Food Science and Nutrition, College of Food, Agricultural and Natural Resource Sciences, University of Minnesota, Twin Cities, Minnesota, USA. xlchen@umn.edu.

Sci Rep ; 8(1): 1679, 2018 01 26.

Article in En | MEDLINE | ID: mdl-29374208

Subject(s)

Cell Differentiation; Cellular Senescence; Down-Regulation; GTP-Binding Proteins/metabolism; Macrophages/physiology; Mitochondria/metabolism; 3T3-L1 Cells; Animals; Cell Respiration; Electron Transport; Mice; Mice, Inbred C57BL; RAW 264.7 Cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down-Regulation / Cell Differentiation / Cellular Senescence / GTP-Binding Proteins / Macrophages / Mitochondria Type of study: Etiology_studies Limits: Animals Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: United States Country of publication: United kingdom

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