Targeting RNA in mammalian systems with small molecules.

Donlic, Anita; Hargrove, Amanda E

Donlic, Anita; Hargrove, Amanda E.

Affiliation

Donlic A; Department of Chemistry, Duke University, Durham, North Carolina.
Hargrove AE; Department of Chemistry, Duke University, Durham, North Carolina.

Wiley Interdiscip Rev RNA ; 9(4): e1477, 2018 07.

Article in En | MEDLINE | ID: mdl-29726113

Subject(s)

RNA Probes/chemistry; RNA Probes/pharmacology; RNA/chemistry; RNA/metabolism; Small Molecule Libraries/chemistry; Small Molecule Libraries/pharmacology; Animals; Humans; Neoplasms/drug therapy; Neoplasms/genetics; Neoplasms/metabolism; Nervous System Diseases/genetics; Nervous System Diseases/metabolism; Phenotype; RNA/genetics; RNA Splice Sites/drug effects; RNA Splice Sites/genetics

Key words

G-quadruplex; RNA; RNA in disease; RNA interactions; RNA structure; RNA therapeutic target; biological systems; chemical probes; expanded repeats; ligand; long non-coding RNA; mammalian; microRNA; small molecule; splice sites

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / RNA Probes / Small Molecule Libraries Limits: Animals / Humans Language: En Journal: Wiley Interdiscip Rev RNA Year: 2018 Document type: Article Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google