Cell-Specific Imd-NF-&#954;B Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection.

Zhai, Zongzhao; Boquete, Jean-Philippe; Lemaitre, Bruno

Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection.

Zhai, Zongzhao; Boquete, Jean-Philippe; Lemaitre, Bruno.

Affiliation

Zhai Z; Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, 1015 Lausanne, Switzerland; Animal Nutrition and Human Health Laboratory, School of Life Sciences, Hunan Normal University, 410081 Changsha, Hunan, China. Electronic address: zongzhao.zhai@foxmail.com.
Boquete JP; Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, 1015 Lausanne, Switzerland.
Lemaitre B; Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, 1015 Lausanne, Switzerland. Electronic address: bruno.lemaitre@epfl.ch.

Immunity ; 48(5): 897-910.e7, 2018 05 15.

Article in En | MEDLINE | ID: mdl-29752064

Subject(s)

Antimicrobial Cationic Peptides/immunology; Bacteria/immunology; Bacterial Infections/immunology; Drosophila Proteins/immunology; Epithelial Cells/immunology; NF-kappa B/immunology; Animals; Animals, Genetically Modified; Antimicrobial Cationic Peptides/metabolism; Bacteria/growth & development; Bacterial Infections/metabolism; Bacterial Infections/microbiology; Drosophila Proteins/genetics; Drosophila Proteins/metabolism; Drosophila melanogaster/immunology; Drosophila melanogaster/metabolism; Drosophila melanogaster/microbiology; Enterocytes/immunology; Enterocytes/metabolism; Enterocytes/microbiology; Epithelial Cells/metabolism; Epithelial Cells/microbiology; GATA Transcription Factors/genetics; GATA Transcription Factors/immunology; GATA Transcription Factors/metabolism; Gene Expression Regulation/immunology; Intestinal Mucosa/cytology; NF-kappa B/metabolism; Signal Transduction/immunology

Key words

Drosophila; GATAe; Imd-NFκB signaling; JNK; enhancer; enteric infection; enterocyte shedding; innate immunity; intestinal epithelial cell

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacteria / Bacterial Infections / NF-kappa B / Antimicrobial Cationic Peptides / Drosophila Proteins / Epithelial Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2018 Document type: Article Country of publication: United States

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