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Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways.
Wu, Xiaxia; Gao, Hongwei; Hou, Ying; Yu, Jie; Sun, Wen; Wang, Ying; Chen, Xiaoyan; Feng, Yulin; Xu, Qiong-Ming; Chen, Xiuping.
Affiliation
  • Wu X; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Gao H; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Hou Y; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Yu J; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Sun W; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Wang Y; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.
  • Chen X; Department of Pathophysiology, Zunyi Medical College, Zunyi, China.
  • Feng Y; State Key Laboratory of Innovative Drug and Efficient Energy-Saving Pharmaceutical Equipment, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.
  • Xu QM; Department of Pharmacognosy, College of Pharmaceutical Science, Soochow University, Suzhou, China.
  • Chen X; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China. Electronic address: xpchen@umac.mo.
Toxicol Appl Pharmacol ; 355: 1-8, 2018 09 15.
Article in En | MEDLINE | ID: mdl-29906494
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Anti-Inflammatory Agents, Non-Steroidal / NF-kappa B / Reactive Oxygen Species / Mitogen-Activated Protein Kinases / Diterpenes / Inflammation / Mitochondria Type of study: Prognostic_studies Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2018 Document type: Article Affiliation country: China Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Anti-Inflammatory Agents, Non-Steroidal / NF-kappa B / Reactive Oxygen Species / Mitogen-Activated Protein Kinases / Diterpenes / Inflammation / Mitochondria Type of study: Prognostic_studies Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2018 Document type: Article Affiliation country: China Country of publication: United States