Beneficial Effect of Silymarin in Pressure Overload Induced Experimental Cardiac Hypertrophy.

Sharma, Basant; Chaube, Udit; Patel, Bhoomika M

Sharma, Basant; Chaube, Udit; Patel, Bhoomika M.

Affiliation

Sharma B; Institute of Pharmacy, Nirma University, Sarkhej-Gandhinagar Highway, Ahmedabad, Gujarat, 382 481, India.
Chaube U; Institute of Pharmacy, Nirma University, Sarkhej-Gandhinagar Highway, Ahmedabad, Gujarat, 382 481, India.
Patel BM; Institute of Pharmacy, Nirma University, Sarkhej-Gandhinagar Highway, Ahmedabad, Gujarat, 382 481, India. drbhoomikampatel@gmail.com.

Cardiovasc Toxicol ; 19(1): 23-35, 2019 02.

Article in En | MEDLINE | ID: mdl-29968071

Subject(s)

Cardiomegaly/prevention & control; Heart Ventricles/drug effects; Silymarin/pharmacology; Animals; Binding Sites; Cardiomegaly/genetics; Cardiomegaly/metabolism; Cardiomegaly/physiopathology; DNA, Mitochondrial/genetics; DNA, Mitochondrial/metabolism; Disease Models, Animal; Female; Heart Ventricles/metabolism; Heart Ventricles/physiopathology; Hemodynamics/drug effects; Male; Mitochondria, Heart/drug effects; Mitochondria, Heart/genetics; Mitochondria, Heart/metabolism; Mitogen-Activated Protein Kinase 11/genetics; Mitogen-Activated Protein Kinase 11/metabolism; Molecular Docking Simulation; Oxidative Stress/drug effects; Protein Binding; Protein Conformation; Rats, Wistar; Signal Transduction/drug effects; Silymarin/metabolism; Ventricular Function, Left/drug effects; Ventricular Remodeling

Key words

Cardiac hypertrophy; MAPK p38 ß; Mitochondrial DNA; Partial abdominal aortic constriction (PAAC); Silymarin

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Silymarin / Cardiomegaly / Heart Ventricles Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cardiovasc Toxicol Journal subject: ANGIOLOGIA / CARDIOLOGIA / TOXICOLOGIA Year: 2019 Document type: Article Affiliation country: India Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google