A bacterial biosensor encoding a genetically modified LuxR receptor exhibits improved detection of Pseudomonas aeruginosa's biomarker molecule 2-aminoacetophenone.

Kviatkovski, I; Yarnitzky, T; Shushan, S; Schwartz-Harari, O; Nir-Paz, R; Helman, Y

Kviatkovski, I; Yarnitzky, T; Shushan, S; Schwartz-Harari, O; Nir-Paz, R; Helman, Y.

Affiliation

Kviatkovski I; Department of Plant Pathology and Microbiology, The Robert H Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, Israel. yael.helman@mail.huji.ac.il.

Chem Commun (Camb) ; 54(66): 9218-9221, 2018 Aug 14.

Article in En | MEDLINE | ID: mdl-30065984

Subject(s)

Acetophenones/blood; Biomarkers/blood; Biosensing Techniques/methods; Binding Sites; Humans; Limit of Detection; Luminescence; Lung Diseases/microbiology; Molecular Docking Simulation; Mutation; Pseudomonas aeruginosa/chemistry; Quorum Sensing/physiology; Repressor Proteins/genetics; Repressor Proteins/metabolism; Respiratory Tract Infections/microbiology; Sputum/microbiology; Trans-Activators/genetics; Trans-Activators/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acetophenones / Biomarkers / Biosensing Techniques Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2018 Document type: Article Affiliation country: Israel Country of publication: United kingdom

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