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Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells.
Trifunov, Selena; Pyle, Angela; Valentino, Maria Lucia; Liguori, Rocco; Yu-Wai-Man, Patrick; Burté, Florence; Duff, Jennifer; Kleinle, Stephanie; Diebold, Isabel; Rugolo, Michela; Horvath, Rita; Carelli, Valerio.
Affiliation
  • Trifunov S; Unit of Neurology Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
  • Pyle A; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, NE1 3BZ, UK.
  • Valentino ML; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, NE1 3BZ, UK.
  • Liguori R; Unit of Neurology Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
  • Yu-Wai-Man P; IRCCS Institute of Neurological Sciences of Bologna (ISNB), Bellaria Hospital, Bologna, Italy.
  • Burté F; Unit of Neurology Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
  • Duff J; IRCCS Institute of Neurological Sciences of Bologna (ISNB), Bellaria Hospital, Bologna, Italy.
  • Kleinle S; NIHR Biomedical Research Centre at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.
  • Diebold I; Cambridge Centre for Brain Repair, Department of Clinical Neurosciences, and MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.
  • Rugolo M; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, NE1 3BZ, UK.
  • Horvath R; Wellcome Trust Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, NE1 3BZ, UK.
  • Carelli V; Medical Genetic Center Munich, 80335, München, Germany.
Sci Rep ; 8(1): 11682, 2018 08 03.
Article in En | MEDLINE | ID: mdl-30076399
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Mitochondrial / Polymerase Chain Reaction / Sequence Deletion / Muscle Cells Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: Italy Country of publication: United kingdom
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Mitochondrial / Polymerase Chain Reaction / Sequence Deletion / Muscle Cells Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: Italy Country of publication: United kingdom