Signaling of free fatty acid receptors 2 and 3 differs in colonic mucosa following selective agonism or coagonism by luminal propionate.

Tough, Iain R; Forbes, Sarah; Cox, Helen M

Tough, Iain R; Forbes, Sarah; Cox, Helen M.

Affiliation

Tough IR; King's College London, Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, London, UK.
Forbes S; King's College London, Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, London, UK.
Cox HM; King's College London, Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, London, UK.

Neurogastroenterol Motil ; 30(12): e13454, 2018 12.

Article in En | MEDLINE | ID: mdl-30136343

Subject(s)

Colon/metabolism; Intestinal Mucosa/metabolism; Propionates/pharmacology; Receptors, Cell Surface/metabolism; Receptors, G-Protein-Coupled/metabolism; Animals; Colon/drug effects; Female; Humans; Intestinal Mucosa/drug effects; Male; Mice; Mice, Inbred C57BL; Middle Aged; Propionates/metabolism; Receptors, Cell Surface/drug effects; Receptors, G-Protein-Coupled/drug effects; Signal Transduction/drug effects; Signal Transduction/physiology

Key words

FFA2 and FFA3; enteric submucosal neurons; enteroendocrine L cells; human colon; mouse colon; propionate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propionates / Colon / Receptors, Cell Surface / Receptors, G-Protein-Coupled / Intestinal Mucosa Limits: Animals / Female / Humans / Male / Middle aged Language: En Journal: Neurogastroenterol Motil Journal subject: GASTROENTEROLOGIA / NEUROLOGIA Year: 2018 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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