Your browser doesn't support javascript.
loading
Nickel-Catalyzed Asymmetric Propargylic Amination of Propargylic Carbonates Bearing an Internal Alkyne Group.
Watanabe, Kouichi; Miyazaki, Yusuke; Okubo, Masataka; Zhou, Biao; Tsuji, Hiroaki; Kawatsura, Motoi.
Affiliation
  • Watanabe K; Department of Chemistry, College of Humanities & Sciences , Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550 , Japan.
  • Miyazaki Y; Department of Chemistry, College of Humanities & Sciences , Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550 , Japan.
  • Okubo M; Department of Chemistry, College of Humanities & Sciences , Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550 , Japan.
  • Zhou B; Department of Chemistry, College of Humanities & Sciences , Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550 , Japan.
  • Tsuji H; Department of Chemistry, College of Humanities & Sciences , Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550 , Japan.
  • Kawatsura M; Department of Chemistry, College of Humanities & Sciences , Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550 , Japan.
Org Lett ; 20(17): 5448-5451, 2018 09 07.
Article in En | MEDLINE | ID: mdl-30141946
We have achieved the nickel-catalyzed asymmetric propargylic amination of propargylic carbonates bearing an internal alkyne group. A wide variety of propargylic carbonates and N-methylaniline derivatives were tolerated under the reaction conditions, providing the corresponding chiral propargylic amines in up to 97% yield with up to 97% ee.
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Org Lett Journal subject: BIOQUIMICA Year: 2018 Document type: Article Affiliation country: Japan Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Org Lett Journal subject: BIOQUIMICA Year: 2018 Document type: Article Affiliation country: Japan Country of publication: United States