Microglia TREM2 is required for electroacupuncture to attenuate neuroinflammation in focal cerebral ischemia/reperfusion rats.

Xu, Hongbei; Mu, Song; Qin, Wenyi

Xu, Hongbei; Mu, Song; Qin, Wenyi.

Affiliation

Xu H; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China; Laboratory Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Mu S; Department of Anus & Intestine Surgery, The Affiliated Hospital of Guizhou Medical University, Guizhou, 550004, China.
Qin W; Department of Integrated Chinese and Western Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. Electronic address: 1023158588@qq.com.

Biochem Biophys Res Commun ; 503(4): 3225-3234, 2018 09 18.

Article in En | MEDLINE | ID: mdl-30149915

Subject(s)

Brain Ischemia/therapy; Electroacupuncture/methods; Inflammation/therapy; Membrane Glycoproteins/genetics; Reperfusion Injury/therapy; Up-Regulation; Animals; Brain Ischemia/complications; Brain Ischemia/genetics; Brain Ischemia/pathology; Gene Silencing; Inflammation/complications; Inflammation/genetics; Inflammation/pathology; Male; Microglia/metabolism; Microglia/pathology; Rats, Sprague-Dawley; Reperfusion Injury/complications; Reperfusion Injury/genetics; Reperfusion Injury/pathology

Key words

Electroacupuncture; Focal cerebral ischemia/reperfusion; NF-κB signaling pathway; Neuroinflammation; PI3K/Akt; TREM2

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Reperfusion Injury / Electroacupuncture / Up-Regulation / Brain Ischemia / Inflammation Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2018 Document type: Article Affiliation country: China

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