Inhibition of cancer stem cells promoted by Pimozide.

Gonçalves, Jussara Maria; Silva, Carolina Amália Barcellos; Rivero, Elena Riet Correa; Cordeiro, Mabel Mariela Rodríguez

Gonçalves, Jussara Maria; Silva, Carolina Amália Barcellos; Rivero, Elena Riet Correa; Cordeiro, Mabel Mariela Rodríguez.

Affiliation

Gonçalves JM; Postgraduate Program in Dentistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Silva CAB; Department of Morphological Sciences, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Rivero ERC; Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Cordeiro MMR; Department of Morphological Sciences, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.

Clin Exp Pharmacol Physiol ; 46(2): 116-125, 2019 02.

Article in En | MEDLINE | ID: mdl-30383889

Subject(s)

Antineoplastic Agents/pharmacology; Neoplastic Stem Cells/drug effects; Pimozide/pharmacology; Animals; Antineoplastic Agents/therapeutic use; Humans; Neoplasms/drug therapy; Neoplasms/metabolism; Neoplasms/pathology; Neoplastic Stem Cells/metabolism; Neoplastic Stem Cells/pathology; Pimozide/therapeutic use

Key words

Pimozide; WD repeat-containing protein 48; cancer; cancer stem cell; signal transducer and activator of transcription; ubiquitine specific protease

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pimozide / Neoplastic Stem Cells / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Clin Exp Pharmacol Physiol Year: 2019 Document type: Article Affiliation country: Brazil Country of publication: Australia

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