Anti-inflammatory fusicoccane-type diterpenoids from the phytopathogenic fungus Alternaria brassicicola.

Li, Fengli; Sun, Weiguang; Guan, Jiankun; Lu, Yuanyuan; Lin, Shuang; Zhang, Sitian; Gao, Weixi; Liu, Junjun; Du, Guang; Wang, Jianping; Zhu, Hucheng; Qi, Changxing; Hu, Zhengxi; Zhang, Yonghui

Li, Fengli; Sun, Weiguang; Guan, Jiankun; Lu, Yuanyuan; Lin, Shuang; Zhang, Sitian; Gao, Weixi; Liu, Junjun; Du, Guang; Wang, Jianping; Zhu, Hucheng; Qi, Changxing; Hu, Zhengxi; Zhang, Yonghui.

Affiliation

Li F; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, People's Republic of China. zhangyh@mails.tjmu.edu.cn hzx616@126.com kingqcx@sina.cn.

Org Biomol Chem ; 16(45): 8751-8760, 2018 11 21.

Article in En | MEDLINE | ID: mdl-30398284

Subject(s)

Alternaria/chemistry; Anti-Inflammatory Agents/pharmacology; Diterpenes/pharmacology; Animals; Anti-Inflammatory Agents/chemistry; Diterpenes/chemistry; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic/drug effects; Interleukin-10/metabolism; Interleukin-1beta/metabolism; Mice; Models, Molecular; Molecular Conformation; Nitric Oxide/metabolism; Nitric Oxide Synthase Type II/metabolism; RAW 264.7 Cells; Transcription Factor RelA/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diterpenes / Alternaria / Anti-Inflammatory Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2018 Document type: Article Country of publication: United kingdom

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