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Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations.
Irmak, Dilber; Fatima, Azra; Gutiérrez-Garcia, Ricardo; Rinschen, Markus M; Wagle, Prerana; Altmüller, Janine; Arrigoni, Laura; Hummel, Barbara; Klein, Corinna; Frese, Christian K; Sawarkar, Ritwick; Rada-Iglesias, Alvaro; Vilchez, David.
Affiliation
  • Irmak D; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, Cologne, Germany.
  • Fatima A; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, Cologne, Germany.
  • Gutiérrez-Garcia R; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, Cologne, Germany.
  • Rinschen MM; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, Cologne, Germany.
  • Wagle P; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, Cologne, Germany.
  • Altmüller J; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Strasse 21, Cologne, Germany.
  • Arrigoni L; Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany.
  • Hummel B; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Klein C; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Frese CK; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, Cologne, Germany.
  • Sawarkar R; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, Cologne, Germany.
  • Rada-Iglesias A; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany.
  • Vilchez D; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, Cologne, Germany.
Hum Mol Genet ; 27(23): 4117-4134, 2018 12 01.
Article in En | MEDLINE | ID: mdl-30452683
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Methyltransferases / Transcription Factors / Huntington Disease / Huntingtin Protein Limits: Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2018 Document type: Article Affiliation country: Germany Country of publication: United kingdom
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Methyltransferases / Transcription Factors / Huntington Disease / Huntingtin Protein Limits: Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2018 Document type: Article Affiliation country: Germany Country of publication: United kingdom