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Histone deacetylase 6 reduction promotes aortic valve calcification via an endoplasmic reticulum stress-mediated osteogenic pathway.
Fu, Zurong; Li, Fei; Jia, Liangliang; Su, Shengan; Wang, Yaping; Cai, Zhejun; Xiang, Meixiang.
Affiliation
  • Fu Z; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Key Lab of Cardiovascular Disease of Zhejiang Province, Hangzhou, Zhejiang, China.
  • Li F; Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Jia L; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Key Lab of Cardiovascular Disease of Zhejiang Province, Hangzhou, Zhejiang, China.
  • Su S; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Key Lab of Cardiovascular Disease of Zhejiang Province, Hangzhou, Zhejiang, China.
  • Wang Y; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Key Lab of Cardiovascular Disease of Zhejiang Province, Hangzhou, Zhejiang, China.
  • Cai Z; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Key Lab of Cardiovascular Disease of Zhejiang Province, Hangzhou, Zhejiang, China; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National
  • Xiang M; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Key Lab of Cardiovascular Disease of Zhejiang Province, Hangzhou, Zhejiang, China. Electronic address: xiangmx@zju.edu.cn.
J Thorac Cardiovasc Surg ; 158(2): 408-417.e2, 2019 08.
Article in En | MEDLINE | ID: mdl-30579537

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortic Valve / Aortic Valve Stenosis / Calcinosis / Endoplasmic Reticulum Stress / Histone Deacetylase 6 Type of study: Etiology_studies / Observational_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: J Thorac Cardiovasc Surg Year: 2019 Document type: Article Affiliation country: China Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortic Valve / Aortic Valve Stenosis / Calcinosis / Endoplasmic Reticulum Stress / Histone Deacetylase 6 Type of study: Etiology_studies / Observational_studies Limits: Female / Humans / Male / Middle aged Language: En Journal: J Thorac Cardiovasc Surg Year: 2019 Document type: Article Affiliation country: China Country of publication: United States