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Hepatic PPARα is critical in the metabolic adaptation to sepsis.
Paumelle, Réjane; Haas, Joel T; Hennuyer, Nathalie; Baugé, Eric; Deleye, Yann; Mesotten, Dieter; Langouche, Lies; Vanhoutte, Jonathan; Cudejko, Céline; Wouters, Kristiaan; Hannou, Sarah Anissa; Legry, Vanessa; Lancel, Steve; Lalloyer, Fanny; Polizzi, Arnaud; Smati, Sarra; Gourdy, Pierre; Vallez, Emmanuelle; Bouchaert, Emmanuel; Derudas, Bruno; Dehondt, Hélène; Gheeraert, Céline; Fleury, Sébastien; Tailleux, Anne; Montagner, Alexandra; Wahli, Walter; Van Den Berghe, Greet; Guillou, Hervé; Dombrowicz, David; Staels, Bart.
Affiliation
  • Paumelle R; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Haas JT; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Hennuyer N; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Baugé E; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Deleye Y; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Mesotten D; Laboratory of Critical Care Medicine, Dept Cellular and Molecular Medicine, KU Leuven, University Hospitals Leuven, Herestraat 49 Bus 503, B-3000 Leuven, Belgium.
  • Langouche L; Laboratory of Critical Care Medicine, Dept Cellular and Molecular Medicine, KU Leuven, University Hospitals Leuven, Herestraat 49 Bus 503, B-3000 Leuven, Belgium.
  • Vanhoutte J; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Cudejko C; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Wouters K; Maastricht University, Dept. of Internal Medicine, Maastricht, The Netherlands.
  • Hannou SA; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Legry V; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Lancel S; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Lalloyer F; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Polizzi A; Institut National de La Recherche Agronomique (INRA), UMR1331 ToxAlim, Toulouse, France.
  • Smati S; Institut National de La Recherche Agronomique (INRA), UMR1331 ToxAlim, Toulouse, France.
  • Gourdy P; Institut National de La Santé et de La Recherche Médicale (INSERM), UMR1048, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France.
  • Vallez E; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Bouchaert E; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Derudas B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Dehondt H; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Gheeraert C; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Fleury S; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Tailleux A; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Montagner A; Institut National de La Santé et de La Recherche Médicale (INSERM), UMR1048, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France; Institut National de La Recherche Agronomique (INRA), UMR1331 ToxAlim, Toulouse, France.
  • Wahli W; Institut National de La Recherche Agronomique (INRA), UMR1331 ToxAlim, Toulouse, France; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Clinical Sciences Building, 11 Mandalay Road, Singapore 308232, Singapore; Center for Integrative Genomics, Université de Lausanne,
  • Van Den Berghe G; Laboratory of Critical Care Medicine, Dept Cellular and Molecular Medicine, KU Leuven, University Hospitals Leuven, Herestraat 49 Bus 503, B-3000 Leuven, Belgium.
  • Guillou H; Institut National de La Recherche Agronomique (INRA), UMR1331 ToxAlim, Toulouse, France.
  • Dombrowicz D; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France.
  • Staels B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011 - EGID, F-59000 Lille, France. Electronic address: bart.staels@pasteur-lille.fr.
J Hepatol ; 70(5): 963-973, 2019 05.
Article in En | MEDLINE | ID: mdl-30677458
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adaptation, Physiological / Sepsis / PPAR alpha / Liver Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2019 Document type: Article Affiliation country: France Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adaptation, Physiological / Sepsis / PPAR alpha / Liver Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2019 Document type: Article Affiliation country: France Country of publication: Netherlands