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Development of the summary of findings table for network meta-analysis.
Yepes-Nuñez, Juan José; Li, Shelly-Anne; Guyatt, Gordon; Jack, Susan M; Brozek, Jan L; Beyene, Joseph; Murad, M Hassan; Rochwerg, Bram; Mbuagbaw, Lawrence; Zhang, Yuan; Flórez, Ivan D; Siemieniuk, Reed A; Sadeghirad, Behnam; Mustafa, Reem; Santesso, Nancy; Schünemann, Holger J.
Affiliation
  • Yepes-Nuñez JJ; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada; School of Medicine, Universidad de los Andes, Carrera 7 No. 116 - 05, Bogotá, D.C., Colombia.
  • Li SA; University of Toronto, 155 College Street, Toronto, Ontario, Canada.
  • Guyatt G; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada; Department of Medicine, McMaster University, Hamilton, Canada.
  • Jack SM; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada; School of Nursing, McMaster University, Hamilton, Ontario, Canada.
  • Brozek JL; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada; Department of Medicine, McMaster University, Hamilton, Canada.
  • Beyene J; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.
  • Murad MH; Mayo Clinic, Evidence-Based Practice Center, 200 1st Street SW, Rochester, MN 55905, USA.
  • Rochwerg B; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada; Department of Medicine, McMaster University, Hamilton, Canada.
  • Mbuagbaw L; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.
  • Zhang Y; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.
  • Flórez ID; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada; Department of Pediatrics, University of Antioquia, Calle 70 No. 52 - 21, Medellín, Colombia.
  • Siemieniuk RA; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.
  • Sadeghirad B; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.
  • Mustafa R; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada; Division of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, KS, USA.
  • Santesso N; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.
  • Schünemann HJ; Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada; Department of Medicine, McMaster University, Hamilton, Canada. Electronic address: schuneh@mcmaster.ca.
J Clin Epidemiol ; 115: 1-13, 2019 11.
Article in En | MEDLINE | ID: mdl-31055177
OBJECTIVES: The aim of the study was to develop a Grading of Recommendations, Assessment, Development and Evaluation (GRADE) summary of findings (SoF) table format that displays the critical information from a network meta-analysis (NMA). STUDY DESIGN AND SETTING: We applied a user experience model for data analysis based on four rounds of semistructured interviews. RESULTS: We interviewed 32 stakeholders who conduct or use MA. Four rounds of interviews produced six candidate NMA-SoF tables. Users found a final NMA-SoF table that included the following components highly acceptable: (1) details of the clinical question (PICO), (2) a plot depicting network geometry, (3) relative and absolute effect estimates, (4) certainty of evidence, (5) ranking of treatments, and (6) interpretation of findings. CONCLUSION: Using stakeholder feedback, we developed a new GRADE NMA-SoF table that includes the relevant components that facilitate understanding NMA findings and health decision-making.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Information Dissemination / Network Meta-Analysis Type of study: Diagnostic_studies / Guideline / Prognostic_studies / Qualitative_research / Systematic_reviews Limits: Humans Language: En Journal: J Clin Epidemiol Journal subject: EPIDEMIOLOGIA Year: 2019 Document type: Article Affiliation country: Colombia Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Information Dissemination / Network Meta-Analysis Type of study: Diagnostic_studies / Guideline / Prognostic_studies / Qualitative_research / Systematic_reviews Limits: Humans Language: En Journal: J Clin Epidemiol Journal subject: EPIDEMIOLOGIA Year: 2019 Document type: Article Affiliation country: Colombia Country of publication: United States