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Macitentan for the treatment of portopulmonary hypertension (PORTICO): a multicentre, randomised, double-blind, placebo-controlled, phase 4 trial.
Sitbon, Olivier; Bosch, Jaume; Cottreel, Emmanuelle; Csonka, Denes; de Groote, Pascal; Hoeper, Marius M; Kim, Nick H; Martin, Nicolas; Savale, Laurent; Krowka, Michael.
Affiliation
  • Sitbon O; Service de Pneumologie, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, INSERM Unité Mixte de Recherche en Santé S_999, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France. Electronic address: olivier.sitbon@u-psud.fr.
  • Bosch J; Hospital Clinic-Institut d'Investigacions Biomèdiques August Pi i Sunyer and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona, Spain; Swiss Liver, Inselspital, Berne University, Bern, Switzerland.
  • Cottreel E; Actelion Pharmaceuticals Ltd, Allschwil, Switzerland.
  • Csonka D; Actelion Pharmaceuticals Ltd, Allschwil, Switzerland.
  • de Groote P; Pôle Cardio-Vasculaire et Pulmonaire, Service de Cardiologie, Centre hospitalier régional universitaire de Lille, Lille, France; Inserm U1167, Institut Pasteur de Lille, Lille, France.
  • Hoeper MM; Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany; German Center of Lung Research, Hannover, Germany.
  • Kim NH; Department of Medicine, University of California San Diego, La Jolla, CA, USA.
  • Martin N; Actelion Pharmaceuticals Ltd, Allschwil, Switzerland.
  • Savale L; Service de Pneumologie, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, INSERM Unité Mixte de Recherche en Santé S_999, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
  • Krowka M; Division of Gastroenterology and Hepatology and Division Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.
Lancet Respir Med ; 7(7): 594-604, 2019 07.
Article in En | MEDLINE | ID: mdl-31178422
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Sulfonamides / Endothelin Receptor Antagonists / Pulmonary Arterial Hypertension / Hypertension, Portal Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Respir Med Year: 2019 Document type: Article Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Sulfonamides / Endothelin Receptor Antagonists / Pulmonary Arterial Hypertension / Hypertension, Portal Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Lancet Respir Med Year: 2019 Document type: Article Country of publication: United kingdom