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Eliminating Preparation of Multisample External Calibration Curves and Dilution of Study Samples Using the Multiple Isotopologue Reaction Monitoring (MIRM) Technique in Quantitative LC-MS/MS Bioanalysis.
Gu, Huidong; Zhao, Yue; DeMichele, Marissa; Zheng, Naiyu; Zhang, Yan J; Pillutla, Renuka; Zeng, Jianing.
Affiliation
  • Gu H; Bioanalytical Sciences, Research & Development , Bristol-Myers Squibb , Route 206 & Province Line Road , Princeton , New Jersey 08543 , United States.
  • Zhao Y; Bioanalytical Sciences, Research & Development , Bristol-Myers Squibb , Route 206 & Province Line Road , Princeton , New Jersey 08543 , United States.
  • DeMichele M; Bioanalytical Sciences, Research & Development , Bristol-Myers Squibb , Route 206 & Province Line Road , Princeton , New Jersey 08543 , United States.
  • Zheng N; Bioanalytical Sciences, Research & Development , Bristol-Myers Squibb , Route 206 & Province Line Road , Princeton , New Jersey 08543 , United States.
  • Zhang YJ; Bioanalytical Sciences, Research & Development , Bristol-Myers Squibb , Route 206 & Province Line Road , Princeton , New Jersey 08543 , United States.
  • Pillutla R; Bioanalytical Sciences, Research & Development , Bristol-Myers Squibb , Route 206 & Province Line Road , Princeton , New Jersey 08543 , United States.
  • Zeng J; Bioanalytical Sciences, Research & Development , Bristol-Myers Squibb , Route 206 & Province Line Road , Princeton , New Jersey 08543 , United States.
Anal Chem ; 91(13): 8652-8659, 2019 07 02.
Article in En | MEDLINE | ID: mdl-31180205
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatography, Liquid / Indicator Dilution Techniques / Tandem Mass Spectrometry / Liquid-Liquid Extraction / Imidazoles / Isotope Labeling Type of study: Prognostic_studies Limits: Humans Language: En Journal: Anal Chem Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatography, Liquid / Indicator Dilution Techniques / Tandem Mass Spectrometry / Liquid-Liquid Extraction / Imidazoles / Isotope Labeling Type of study: Prognostic_studies Limits: Humans Language: En Journal: Anal Chem Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States