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Biliary reconstruction before clamp removal to avoid portal vein thrombosis in pediatric living-donor liver transplantation using hyper-reduced left lateral segment grafts: A novel technical strategy.
Glinka, Juan; de Santibañes, Martin; Biagiola, David; D Agostino, Daniel; Ardiles, Victoria; Ciardullo, Miguel; Mattera, Juan; Pekolj, Juan; de Santibañes, Eduardo.
Affiliation
  • Glinka J; Department of General Surgery, Hepato-bilio-pancreatic & Liver Transplantation Unit Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
  • de Santibañes M; Department of General Surgery, Hepato-bilio-pancreatic & Liver Transplantation Unit Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
  • Biagiola D; Department of General Surgery, Hepato-bilio-pancreatic & Liver Transplantation Unit Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
  • D Agostino D; Pediatric Gastroenterology-Hepatology Division, Liver-Intestinal Transplantation Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
  • Ardiles V; Department of General Surgery, Hepato-bilio-pancreatic & Liver Transplantation Unit Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
  • Ciardullo M; Department of General Surgery, Hepato-bilio-pancreatic & Liver Transplantation Unit Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
  • Mattera J; Department of General Surgery, Hepato-bilio-pancreatic & Liver Transplantation Unit Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
  • Pekolj J; Department of General Surgery, Hepato-bilio-pancreatic & Liver Transplantation Unit Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
  • de Santibañes E; Department of General Surgery, Hepato-bilio-pancreatic & Liver Transplantation Unit Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.
Pediatr Transplant ; 23(6): e13516, 2019 09.
Article in En | MEDLINE | ID: mdl-31215179
LT has become the treatment of choice for children with end-stage liver disease. The scarcity of donors and the considerable mortality on waiting lists have propelled the related living-donor techniques, especially in small children. This population need smaller and good quality grafts and are usually candidates to receive a LLS from a related donor. Many times this grafts are still large and do not fit in the receptor's abdomen, so a further hyper-reduction may be required. Despite all advances in LT field, vascular complications still occur in a considerable proportion remaining as a significant cause of morbidity, graft loss, and mortality. Technical issues currently play an essential role in its genesis. The widely spread technique for biliary and vascular reconstruction in living donor LT (LDLT) nowadays implies removal of the portal vein (PV) clamp after the venous anastomosis, then the arterial reconstruction is done, followed by the biliary reconstruction. However, due to the posterior location of the LLS bile duct, for its reconstruction, a rotation of the liver is required risking a potential transient PV occlusion leading to thrombosis afterward. We describe a new technique that involves performing biliary reconstruction after the PV anastomosis and before removing the vascular clamp, thus allowing to freely rotate the liver with less risk of PV occlusion and thrombosis.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Bile Ducts / Biliary Tract / Liver Transplantation / End Stage Liver Disease Type of study: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Limits: Child, preschool / Humans / Infant Language: En Journal: Pediatr Transplant Journal subject: PEDIATRIA / TRANSPLANTE Year: 2019 Document type: Article Affiliation country: Argentina Country of publication: Denmark

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Bile Ducts / Biliary Tract / Liver Transplantation / End Stage Liver Disease Type of study: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Limits: Child, preschool / Humans / Infant Language: En Journal: Pediatr Transplant Journal subject: PEDIATRIA / TRANSPLANTE Year: 2019 Document type: Article Affiliation country: Argentina Country of publication: Denmark