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Geniposide protected hepatocytes from acetaminophen hepatotoxicity by down-regulating CYP 2E1 expression and inhibiting TLR 4/NF-κB signaling pathway.
Yang, Sen; Kuang, Ge; Jiang, Rong; Wu, Shengwang; Zeng, Tao; Wang, Yuanyuan; Xu, Fangzhi; Xiong, Lingyi; Gong, Xia; Wan, Jingyuan.
Affiliation
  • Yang S; Department of Pharmacology, Chongqing Medical University, Chongqing 400016, China.
  • Kuang G; Department of Pharmacology, Chongqing Medical University, Chongqing 400016, China.
  • Jiang R; Laboratory of Stem Cell and Tissue Engineering, Chongqing Medical University, Chongqing 400016, China.
  • Wu S; Department of Anatomy, Chongqing Medical University, Chongqing 400016, China.
  • Zeng T; Medical College, Jingchu University of Technology, Jingmen, Hubei 448000, China.
  • Wang Y; Department of Pharmacology, Chongqing Medical University, Chongqing 400016, China.
  • Xu F; Department of Pharmacology, Chongqing Medical University, Chongqing 400016, China.
  • Xiong L; Department of Pharmacology, Chongqing Medical University, Chongqing 400016, China.
  • Gong X; Department of Anatomy, Chongqing Medical University, Chongqing 400016, China. Electronic address: xiagong@cqmu.edu.cn.
  • Wan J; Department of Pharmacology, Chongqing Medical University, Chongqing 400016, China. Electronic address: jywan@cqmu.edu.cn.
Int Immunopharmacol ; 74: 105625, 2019 Sep.
Article in En | MEDLINE | ID: mdl-31302451
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Protective Agents / Hepatocytes / Iridoids / Toll-Like Receptor 4 Limits: Animals Language: En Journal: Int Immunopharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Year: 2019 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Protective Agents / Hepatocytes / Iridoids / Toll-Like Receptor 4 Limits: Animals Language: En Journal: Int Immunopharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Year: 2019 Document type: Article Affiliation country: China