Genetically Encoded Halide Sensor-Based Fluorescent Assay for Rapid Screening of Glutamate Transport and Inhibition.

Zielewicz, Laura; Grewer, Christof

Zielewicz, Laura; Grewer, Christof.

Affiliation

Zielewicz L; Department of Chemistry , Binghamton University , 4400 Vestal Parkway East , Binghamton , New York 13902 , United States.
Grewer C; Department of Chemistry , Binghamton University , 4400 Vestal Parkway East , Binghamton , New York 13902 , United States.

ACS Sens ; 4(9): 2358-2366, 2019 09 27.

Article in En | MEDLINE | ID: mdl-31393114

Subject(s)

Glutamic Acid/metabolism; Halogens/metabolism; Optical Imaging/methods; Bacterial Proteins/genetics; Biological Transport; Excitatory Amino Acid Transporter 2/antagonists & inhibitors; Excitatory Amino Acid Transporter 2/genetics; Excitatory Amino Acid Transporter 2/metabolism; Excitatory Amino Acid Transporter 3/antagonists & inhibitors; Excitatory Amino Acid Transporter 3/genetics; Excitatory Amino Acid Transporter 3/metabolism; HEK293 Cells; Humans; Luminescent Proteins/genetics; Time Factors

Key words

binding; electrophysiology; fluorescence; glutamate transporter; inhibitor; method development

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glutamic Acid / Optical Imaging / Halogens Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: ACS Sens Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States

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