Postprandial effects on electrolyte homeostasis in the kidney.
Am J Physiol Renal Physiol
; 317(6): F1405-F1408, 2019 12 01.
Article
in En
| MEDLINE
| ID: mdl-31566434
ABSTRACT
Insulin is known to be an important regulator of a number of different channels and transporters in the kidney, but its role in the kidney to prevent Na+ and volume loss during the osmotic load after a meal has only recently been validated. With increasing numbers of people suffering from diabetes and hypertension, furthering our understanding of insulin signaling and renal Na+ handling in both normal and diseased states is essential for improving patient treatments and outcomes. The present review is focused on postprandial effects on Na+ reabsorption in the kidney and the role of the epithelial Na+ channels as an important channel contributing to insulin-mediated Na+ reclamation.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Water-Electrolyte Balance
/
Postprandial Period
/
Kidney
Limits:
Animals
/
Humans
Language:
En
Journal:
Am J Physiol Renal Physiol
Journal subject:
FISIOLOGIA
/
NEFROLOGIA
Year:
2019
Document type:
Article