Your browser doesn't support javascript.
loading
Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies.
Chavarria, Daniel; Fernandes, Carlos; Silva, Vera; Silva, Catia; Gil-Martins, Eva; Soares, Pedro; Silva, Tiago; Silva, Renata; Remião, Fernando; Oliveira, Paulo J; Borges, Fernanda.
Affiliation
  • Chavarria D; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal; CNC - Center for Neuroscience and Cell Biology, University of Coimbra, UC Biotech, Biocant Park, Cantanhede, Portugal.
  • Fernandes C; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal.
  • Silva V; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal; UCIBIO-REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
  • Silva C; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal.
  • Gil-Martins E; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal; UCIBIO-REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
  • Soares P; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal.
  • Silva T; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal; CNC - Center for Neuroscience and Cell Biology, University of Coimbra, UC Biotech, Biocant Park, Cantanhede, Portugal.
  • Silva R; UCIBIO-REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
  • Remião F; UCIBIO-REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal.
  • Oliveira PJ; CNC - Center for Neuroscience and Cell Biology, University of Coimbra, UC Biotech, Biocant Park, Cantanhede, Portugal.
  • Borges F; CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal. Electronic address: fborges@fc.up.pt.
Eur J Med Chem ; 185: 111770, 2020 Jan 01.
Article in En | MEDLINE | ID: mdl-31711793
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Drug Design / Neuroprotective Agents / Alkaloids / Benzodioxoles / Polyunsaturated Alkamides / Monoamine Oxidase / Monoamine Oxidase Inhibitors Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Affiliation country: Portugal Country of publication: France
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Drug Design / Neuroprotective Agents / Alkaloids / Benzodioxoles / Polyunsaturated Alkamides / Monoamine Oxidase / Monoamine Oxidase Inhibitors Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Affiliation country: Portugal Country of publication: France