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Metabolic pathway analyses identify proline biosynthesis pathway as a promoter of liver tumorigenesis.
Ding, Zhaobing; Ericksen, Russell E; Escande-Beillard, Nathalie; Lee, Qian Yi; Loh, Abigail; Denil, Simon; Steckel, Michael; Haegebarth, Andrea; Wai Ho, Timothy Shen; Chow, Pierce; Toh, Han Chong; Reversade, Bruno; Gruenewald, Sylvia; Han, Weiping.
Affiliation
  • Ding Z; Singapore Bioimaging Consortium, A*STAR, Singapore 138667, Singapore.
  • Ericksen RE; Singapore Bioimaging Consortium, A*STAR, Singapore 138667, Singapore.
  • Escande-Beillard N; Institute of Medical Biology, A*STAR, Singapore 138648, Singapore.
  • Lee QY; Singapore Bioimaging Consortium, A*STAR, Singapore 138667, Singapore.
  • Loh A; Institute of Medical Biology, A*STAR, Singapore 138648, Singapore; Institute of Molecular and Cell Biology, A*STAR, Singapore 138673, Singapore.
  • Denil S; Institute of Medical Biology, A*STAR, Singapore 138648, Singapore.
  • Steckel M; Bayer AG, Preclinical Research, Pharmaceuticals, Müllerstrasse 178, 13353 Berlin, Germany.
  • Haegebarth A; Bayer AG, Preclinical Research, Pharmaceuticals, Müllerstrasse 178, 13353 Berlin, Germany.
  • Wai Ho TS; National Cancer Center and Singapore General Hospital, Singapore 169610, Singapore.
  • Chow P; National Cancer Center and Singapore General Hospital, Singapore 169610, Singapore.
  • Toh HC; National Cancer Center and Singapore General Hospital, Singapore 169610, Singapore.
  • Reversade B; Institute of Medical Biology, A*STAR, Singapore 138648, Singapore; Institute of Molecular and Cell Biology, A*STAR, Singapore 138673, Singapore.
  • Gruenewald S; Bayer AG, Preclinical Research, Pharmaceuticals, Müllerstrasse 178, 13353 Berlin, Germany.
  • Han W; Singapore Bioimaging Consortium, A*STAR, Singapore 138667, Singapore; Institute of Molecular and Cell Biology, A*STAR, Singapore 138673, Singapore. Electronic address: wh10@cornell.edu.
J Hepatol ; 72(4): 725-735, 2020 04.
Article in En | MEDLINE | ID: mdl-31726117
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proline / Signal Transduction / Carcinoma, Hepatocellular / Carcinogenesis / Liver Neoplasms / Liver Neoplasms, Experimental Type of study: Prognostic_studies Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2020 Document type: Article Affiliation country: Singapore
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proline / Signal Transduction / Carcinoma, Hepatocellular / Carcinogenesis / Liver Neoplasms / Liver Neoplasms, Experimental Type of study: Prognostic_studies Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2020 Document type: Article Affiliation country: Singapore