Alpha-pinene promotes osteoblast differentiation and attenuates TNF&#945;-induced inhibition of differentiation in MC3T3-E1 pre-osteoblasts.

Min, Hyeon-Young; Son, Hyo-Eun; Jang, Won-Gu

Alpha-pinene promotes osteoblast differentiation and attenuates TNFα-induced inhibition of differentiation in MC3T3-E1 pre-osteoblasts.

Min, Hyeon-Young; Son, Hyo-Eun; Jang, Won-Gu.

Affiliation

Min HY; Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan, Korea.
Son HE; Research Institute of Anti-Aging, Daegu University, Gyeongsan, Korea.
Jang WG; Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan, Korea.

Clin Exp Pharmacol Physiol ; 47(5): 831-837, 2020 05.

Article in En | MEDLINE | ID: mdl-31883130

Subject(s)

Bicyclic Monoterpenes/pharmacology; Cell Differentiation/drug effects; Osteoblasts/drug effects; Osteogenesis/drug effects; Tumor Necrosis Factor-alpha/pharmacology; 3T3 Cells; Alkaline Phosphatase/metabolism; Animals; Calcification, Physiologic/drug effects; Extracellular Matrix/drug effects; Extracellular Matrix/metabolism; Mice; Osteoblasts/metabolism; Phosphorylation; Smad1 Protein/metabolism; Smad5 Protein/metabolism; Smad8 Protein/metabolism

Key words

osteoblast differentiation; tumour necrosis factor-alpha; α-Pinene

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoblasts / Osteogenesis / Cell Differentiation / Tumor Necrosis Factor-alpha / Bicyclic Monoterpenes Limits: Animals Language: En Journal: Clin Exp Pharmacol Physiol Year: 2020 Document type: Article Country of publication: Australia

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