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New modification strategy of matrine as Hsp90 inhibitors based on its specific L conformation for cancer treatment.
Xu, Yiming; Jing, Dewang; Zhao, Dong; Wu, Yongji; Xing, Lu; Ur Rashid, Haroon; Wang, Haodong; Wang, Lisheng; Cao, Huiling.
Affiliation
  • Xu Y; Medicinal College, Guangxi University, Nanning 530004, China; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
  • Jing D; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
  • Zhao D; Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic Translational Medicine, Xi'an Medical University, Xi'an 710021, China.
  • Wu Y; College of Veterinary Medicine, Northwest A&F University, Yangling 712100, China.
  • Xing L; Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic Translational Medicine, Xi'an Medical University, Xi'an 710021, China.
  • Ur Rashid H; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China; Department of Chemistry, Sarhad University of Science & Information Technology, Peshawar, Khyber Pakhtunkhwa 25120, Pakistan.
  • Wang H; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
  • Wang L; Medicinal College, Guangxi University, Nanning 530004, China. Electronic address: lswang@gxu.edu.cn.
  • Cao H; Shaanxi Key Laboratory of Ischemic Cardiovascular Disease, Institute of Basic Translational Medicine, Xi'an Medical University, Xi'an 710021, China. Electronic address: caohuiling_jzs@xiyi.edu.cn.
Bioorg Med Chem ; 28(4): 115305, 2020 02 15.
Article in En | MEDLINE | ID: mdl-31928863
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolizines / HSP90 Heat-Shock Proteins / Alkaloids / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2020 Document type: Article Affiliation country: China Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolizines / HSP90 Heat-Shock Proteins / Alkaloids / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2020 Document type: Article Affiliation country: China Country of publication: United kingdom