Pathology of BRCA1- and BRCA2-associated Breast Cancers: Known and Less Known Connections.

Fountzilas, Elena; Konstantopoulou, Irene; Vagena, Andromahi; Apostolou, Paraskevi; Papadimitriou, Christos; Christodoulou, Christos; Tryfonopoulos, Dimitrios; Manousou, Kyriaki; Delimitsou, Angeliki; Papamentzelopoulou, Myrto; Fountzilas, Georgios; Yannoukakos, Drakoulis; Fostira, Florentia

Fountzilas, Elena; Konstantopoulou, Irene; Vagena, Andromahi; Apostolou, Paraskevi; Papadimitriou, Christos; Christodoulou, Christos; Tryfonopoulos, Dimitrios; Manousou, Kyriaki; Delimitsou, Angeliki; Papamentzelopoulou, Myrto; Fountzilas, Georgios; Yannoukakos, Drakoulis; Fostira, Florentia.

Affiliation

Fountzilas E; Department of Investigational Cancer Therapeutics, MD Anderson Cancer Center, Houston, TX.
Konstantopoulou I; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece.
Vagena A; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece.
Apostolou P; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece.
Papadimitriou C; Oncology Unit, Second Department of Surgery, "Aretaieion" Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Christodoulou C; Second Department of Medical Oncology, Metropolitan Hospital, Piraeus, Greece.
Tryfonopoulos D; Second Oncological Clinic, Agios Savvas Hospital, Athens, Greece.
Manousou K; Section of Biostatistics, Hellenic Cooperative Oncology Group, Athens, Greece.
Delimitsou A; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece.
Papamentzelopoulou M; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece.
Fountzilas G; Laboratory of Molecular Oncology, Hellenic Foundation for Cancer Research/Aristotle University of Thessaloniki, Thessaloniki, Greece.
Yannoukakos D; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece.
Fostira F; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Athens, Greece. Electronic address: florentia_fostira@hotmail.com.

Clin Breast Cancer ; 20(2): 152-159, 2020 04.

Article in En | MEDLINE | ID: mdl-31980407

Subject(s)

Breast Neoplasms/genetics; Breast/pathology; Carcinoma, Ductal, Breast/genetics; Carcinoma, Lobular/genetics; Carcinoma, Medullary/genetics; Neoplasms, Second Primary/genetics; Adult; Aged; BRCA1 Protein/genetics; BRCA2 Protein/genetics; Breast/surgery; Breast Neoplasms/mortality; Breast Neoplasms/pathology; Breast Neoplasms/therapy; Carcinoma, Ductal, Breast/mortality; Carcinoma, Ductal, Breast/pathology; Carcinoma, Ductal, Breast/therapy; Carcinoma, Lobular/mortality; Carcinoma, Lobular/pathology; Carcinoma, Lobular/therapy; Carcinoma, Medullary/mortality; Carcinoma, Medullary/pathology; Carcinoma, Medullary/therapy; Chemotherapy, Adjuvant; DNA Mutational Analysis; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genetic Testing/statistics & numerical data; Greece; Heterozygote; Humans; Kaplan-Meier Estimate; Mastectomy; Middle Aged; Mutation; Neoplasm Grading; Neoplasms, Second Primary/mortality; Neoplasms, Second Primary/pathology; Neoplasms, Second Primary/therapy; Radiotherapy, Adjuvant; Retrospective Studies; Treatment Outcome; Young Adult

Key words

HER2; Hereditary breast cancer; Mutations; Overall survival; TNBC

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast / Breast Neoplasms / Neoplasms, Second Primary / Carcinoma, Medullary / Carcinoma, Lobular / Carcinoma, Ductal, Breast Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Country/Region as subject: Europa Language: En Journal: Clin Breast Cancer Journal subject: NEOPLASIAS Year: 2020 Document type: Article

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