Analysis of DNA Interstrand Cross-Links and their Repair by Modified Comet Assay.

Swift, Lonnie P; Castle, Lianne; McHugh, Peter J

Swift, Lonnie P; Castle, Lianne; McHugh, Peter J.

Affiliation

Swift LP; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. lonnie.swift@imm.ox.ac.uk.
Castle L; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
McHugh PJ; Department of Oncology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. peter.mchugh@imm.ox.ac.uk.

Methods Mol Biol ; 2119: 79-88, 2020.

Article in En | MEDLINE | ID: mdl-31989516

Subject(s)

Antineoplastic Agents/pharmacology; Comet Assay; DNA Damage; DNA Repair/drug effects; DNA; Animals; Antineoplastic Agents/pharmacokinetics; Cell Line; DNA/analysis; DNA/metabolism; Humans

Key words

DNA damage; DNA repair; Electrophoresis; Fanconi anemia; Interstrand cross-links; Unhooking

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / DNA / Comet Assay / DNA Repair / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: United kingdom Country of publication: United States

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