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Bilateral pseudoangiomatous stromal hyperplasia in childhood gigantomastia: A challenge in reconstruction and management.
Morone, Isadora; de Andrade, Guilherme Pansardi; Cardoso, Paola Soares; de Oliveira, Afrânio Coelho; Clímaco, Flávia; Medeiros, João; Franco, Diogo.
Affiliation
  • Morone I; Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), Brazil.
  • de Andrade GP; Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), Brazil.
  • Cardoso PS; Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), Brazil.
  • de Oliveira AC; Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), Brazil.
  • Clímaco F; Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), Brazil.
  • Medeiros J; Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), Brazil.
  • Franco D; Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro (HUCFF-UFRJ), Brazil.
JPRAS Open ; 19: 106-110, 2019 Mar.
Article in En | MEDLINE | ID: mdl-32158862
The presence of mammary nodules during childhood and adolescence is somewhat unusual, generally consisting of benign lesions. Despite the range of possible diagnoses, they are generally similar in clinical terms. In the rare cases where these lesions constitute a case of gigantomastia, the differential diagnosis must be between juvenile fibroadenomatosis, phyllodes tumours and other even less common diseases of the mammary gland, such as Pseudoangiomatous Stromal Hyperplasia (PASH). This is caused by the exacerbated proliferation of mature fibroblasts and myofibroblasts, with the trigger factor still unknown. This study reports on a rare case of bilateral PASH in a young patient, describing its diagnosis and the surgical technique used.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: JPRAS Open Year: 2019 Document type: Article Affiliation country: Brazil Country of publication: Netherlands

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: JPRAS Open Year: 2019 Document type: Article Affiliation country: Brazil Country of publication: Netherlands