High-Throughput Cryo-EM Enabled by User-Free Preprocessing Routines.

Li, Yilai; Cash, Jennifer N; Tesmer, John J G; Cianfrocco, Michael A

Li, Yilai; Cash, Jennifer N; Tesmer, John J G; Cianfrocco, Michael A.

Affiliation

Li Y; Life Sciences Institute, Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA.
Cash JN; Life Sciences Institute, Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA.
Tesmer JJG; Departments of Biological Sciences and of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN, USA.
Cianfrocco MA; Life Sciences Institute, Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA. Electronic address: mcianfro@umich.edu.

Structure ; 28(7): 858-869.e3, 2020 07 07.

Article in En | MEDLINE | ID: mdl-32294468

Subject(s)

Cryoelectron Microscopy/methods; High-Throughput Screening Assays/methods; Image Processing, Computer-Assisted/methods; Cryoelectron Microscopy/standards; Deep Learning; High-Throughput Screening Assays/standards; Image Processing, Computer-Assisted/standards; Protein Conformation

Key words

automatic; cryo-EM; deep learning;; pipeline

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Image Processing, Computer-Assisted / Cryoelectron Microscopy / High-Throughput Screening Assays Type of study: Prognostic_studies Language: En Journal: Structure Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA / BIOTECNOLOGIA Year: 2020 Document type: Article Affiliation country: United States

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