Sustainable release of vancomycin from micro-arc oxidised 3D-printed porous Ti6Al4V for treating methicillin-resistant Staphylococcus aureus bone infection and enhancing osteogenesis in a rabbit tibia osteomyelitis model.

Zhang, Teng; Wei, Qingguang; Zhou, Hua; Zhou, Wenhao; Fan, Daoyang; Lin, Xinhong; Jing, Zehao; Cai, Hong; Cheng, Yan; Liu, Xiaoguang; Li, Weishi; Song, Chunli; Tian, Yun; Xu, Nanfang; Zheng, Yufeng; Liu, Zhongjun

Zhang, Teng; Wei, Qingguang; Zhou, Hua; Zhou, Wenhao; Fan, Daoyang; Lin, Xinhong; Jing, Zehao; Cai, Hong; Cheng, Yan; Liu, Xiaoguang; Li, Weishi; Song, Chunli; Tian, Yun; Xu, Nanfang; Zheng, Yufeng; Liu, Zhongjun.

Affiliation

Zhang T; Department of Orthopedics, Peking University Third Hospital, Beijing 100191, People's Republic of China. puthztlzj@163.com.

Biomater Sci ; 8(11): 3106-3115, 2020 Jun 07.

Article in En | MEDLINE | ID: mdl-32350485

Subject(s)

Anti-Bacterial Agents/administration & dosage; Methicillin-Resistant Staphylococcus aureus; Osteomyelitis/drug therapy; Staphylococcal Infections/drug therapy; Titanium/administration & dosage; Vancomycin/administration & dosage; Alloys; Animals; Delayed-Action Preparations/administration & dosage; Male; Osteogenesis/drug effects; Osteomyelitis/diagnostic imaging; Osteomyelitis/microbiology; Osteomyelitis/pathology; Oxidation-Reduction; Porosity; Printing, Three-Dimensional; Rabbits; Staphylococcal Infections/diagnostic imaging; Staphylococcal Infections/microbiology; Staphylococcal Infections/pathology; Tibia/diagnostic imaging; Tibia/drug effects; Tibia/microbiology; Tibia/pathology; Tissue Scaffolds; X-Ray Microtomography

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteomyelitis / Staphylococcal Infections / Titanium / Vancomycin / Methicillin-Resistant Staphylococcus aureus / Anti-Bacterial Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Biomater Sci Year: 2020 Document type: Article Country of publication: United kingdom

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