Propofol suppresses the progression of non­small cell lung cancer via downregulation of the miR­21­5p/MAPK10 axis.

Wu, Xinhua; Li, Xuebin; Xu, Guiping

Propofol suppresses the progression of nonsmall cell lung cancer via downregulation of the miR215p/MAPK10 axis.

Wu, Xinhua; Li, Xuebin; Xu, Guiping.

Affiliation

Wu X; Department of Anesthesiology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, Xinjiang UygurAutonomous Region, P.R.China.
Li X; Department of Anesthesiology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, Xinjiang UygurAutonomous Region, P.R.China.
Xu G; Department of Anesthesiology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, Xinjiang UygurAutonomous Region, P.R.China.

Oncol Rep ; 44(2): 487-498, 2020 08.

Article in En | MEDLINE | ID: mdl-32468043

Subject(s)

Carcinoma, Non-Small-Cell Lung/genetics; Down-Regulation; MicroRNAs/genetics; Mitogen-Activated Protein Kinase 11/genetics; Propofol/pharmacology; 3' Untranslated Regions; A549 Cells; Adult; Carcinoma, Non-Small-Cell Lung/metabolism; Carcinoma, Non-Small-Cell Lung/pathology; Cell Line, Tumor; Cell Proliferation/drug effects; Cell Survival/drug effects; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms/genetics; Lung Neoplasms/metabolism; Lung Neoplasms/pathology; Male; MicroRNAs/metabolism; Middle Aged; Mitogen-Activated Protein Kinase 11/metabolism

Key words

lung cancer; propofol; mitogen-activated protein kinase 10; microRNA-21-5p

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down-Regulation / Propofol / Carcinoma, Non-Small-Cell Lung / MicroRNAs / Mitogen-Activated Protein Kinase 11 Type of study: Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2020 Document type: Article Country of publication: Greece

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