The Association Between Concurrence of Infection and the Onset of Severe Eruption or Liver Injury in Patients Using Antipyretic Analgesics: A Matched, Nested Case-Control Study.

Imatoh, Takuya; Sai, Kimie; Saito, Yoshiro

Imatoh, Takuya; Sai, Kimie; Saito, Yoshiro.

Affiliation

Imatoh T; Division of Medicinal Safety Science, National Institute of Health Sciences, Kanagawa, Japan.
Sai K; Division of Medicinal Safety Science, National Institute of Health Sciences, Kanagawa, Japan.
Saito Y; Division of Medicinal Safety Science, National Institute of Health Sciences, Kanagawa, Japan.

J Clin Pharmacol ; 60(9): 1177-1184, 2020 09.

Article in En | MEDLINE | ID: mdl-32521061

Subject(s)

Analgesics, Non-Narcotic/adverse effects; Antipyretics/adverse effects; Bacterial Infections; Chemical and Drug Induced Liver Injury/etiology; Mycoses; Stevens-Johnson Syndrome/etiology; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic/therapeutic use; Antipyretics/therapeutic use; Bacterial Infections/drug therapy; Databases, Factual; Female; Humans; Japan/epidemiology; Male; Middle Aged; Mycoses/drug therapy; Odds Ratio; Regression Analysis; Retrospective Studies

Key words

Stevens-Johnson syndrome; infectious disease; liver injury; pharmacoepidemiogy; toxic epidermal necrosis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Infections / Stevens-Johnson Syndrome / Analgesics, Non-Narcotic / Chemical and Drug Induced Liver Injury / Antipyretics / Mycoses Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: J Clin Pharmacol Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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