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Novel Compounds Identified by Structure-Based Prion Disease Drug Discovery Using In Silico Screening Delay the Progression of an Illness in Prion-Infected Mice.
Ishibashi, Daisuke; Ishikawa, Takeshi; Mizuta, Satoshi; Tange, Hiroya; Nakagaki, Takehiro; Hamada, Tsuyoshi; Nishida, Noriyuki.
Affiliation
  • Ishibashi D; Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan. dishi@fukuoka-u.ac.jp.
  • Ishikawa T; Department of Immunological and Molecular Pharmacology, Faculty of Pharmaceutical Science, Fukuoka University, 8-19-1 Nanakuma Jonan-ku, Fukuoka, 814-0180, Japan. dishi@fukuoka-u.ac.jp.
  • Mizuta S; Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.
  • Tange H; Department of Chemistry, Biotechnology, and Chemical Engineering, Graduate School of Science and Engineering, Kagoshima University, 1-21-40 Korimoto, Kagoshima, 890-0065, Japan.
  • Nakagaki T; Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.
  • Hamada T; Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.
  • Nishida N; Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.
Neurotherapeutics ; 17(4): 1836-1849, 2020 10.
Article in En | MEDLINE | ID: mdl-32767031
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Computer Simulation / Prion Diseases / Disease Progression / Drug Discovery / Prion Proteins Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals / Humans / Male Language: En Journal: Neurotherapeutics Journal subject: NEUROLOGIA Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Computer Simulation / Prion Diseases / Disease Progression / Drug Discovery / Prion Proteins Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals / Humans / Male Language: En Journal: Neurotherapeutics Journal subject: NEUROLOGIA Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United States