Botulinum Toxin Type A Possibly Affects Ca<sub>v</sub>3.2 Calcium Channel Subunit in Rats with Spinal Cord Injury-Induced Muscle Spasticity.

Ma, Kening; Zhu, Dan; Zhang, Chunguo; Lv, Lijie

Botulinum Toxin Type A Possibly Affects Ca_v3.2 Calcium Channel Subunit in Rats with Spinal Cord Injury-Induced Muscle Spasticity.

Ma, Kening; Zhu, Dan; Zhang, Chunguo; Lv, Lijie.

Affiliation

Ma K; Department of Pain Medicine, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Zhu D; Department of Neurologic Medicine, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Zhang C; Department of Pain Medicine, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.
Lv L; Department of Medicine and Pension, The First Hospital of Jilin University, Changchun 130021, People's Republic of China.

Drug Des Devel Ther ; 14: 3029-3041, 2020.

Article in En | MEDLINE | ID: mdl-32801642

Subject(s)

Botulinum Toxins, Type A/pharmacology; Calcium Channel Blockers/pharmacology; Calcium Channels, T-Type/metabolism; Muscle Spasticity/drug therapy; Spinal Cord Injuries/drug therapy; Animals; Behavior, Animal/drug effects; Calcium Channels, T-Type/genetics; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Muscle Spasticity/metabolism; Rats; Rats, Wistar; Spinal Cord Injuries/metabolism; Swimming

Key words

Cav3.2 calcium channel; botulinum toxin type A; muscle spasticity; rat model; spinal cord injuries

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Injuries / Calcium Channel Blockers / Botulinum Toxins, Type A / Calcium Channels, T-Type / Muscle Spasticity Limits: Animals Language: En Journal: Drug Des Devel Ther Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2020 Document type: Article Country of publication: New Zealand

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