2'-Deoxycoformycin (pentostatin) for lymphoid malignancies. Rational development of an active new drug.

O'Dwyer, P J; Wagner, B; Leyland-Jones, B; Wittes, R E; Cheson, B D; Hoth, D F

O'Dwyer, P J; Wagner, B; Leyland-Jones, B; Wittes, R E; Cheson, B D; Hoth, D F.

Affiliation

O'Dwyer PJ; Fox Chase Cancer Center, Philadelphia, Pennsylvania.

Ann Intern Med ; 108(5): 733-43, 1988 May.

Article in En | MEDLINE | ID: mdl-3282467

Subject(s)

Antimetabolites, Antineoplastic/therapeutic use; Coformycin/therapeutic use; Leukemia/drug therapy; Lymphoma/drug therapy; Ribonucleosides/therapeutic use; Adenosine Deaminase Inhibitors; Animals; Antimetabolites, Antineoplastic/adverse effects; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Coformycin/adverse effects; Coformycin/analogs & derivatives; Coformycin/pharmacokinetics; Coformycin/pharmacology; Drug Evaluation; Humans; Immunosuppressive Agents; Pentostatin

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Collection: 01-internacional Database: MEDLINE Main subject: Ribonucleosides / Leukemia / Coformycin / Lymphoma / Antimetabolites, Antineoplastic Limits: Animals / Humans Language: En Journal: Ann Intern Med Year: 1988 Document type: Article Country of publication: United States

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