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Epigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes.
García-Calzón, Sonia; Perfilyev, Alexander; Martinell, Mats; Ustinova, Monta; Kalamajski, Sebastian; Franks, Paul W; Bacos, Karl; Elbere, Ilze; Pihlajamäki, Jussi; Volkov, Petr; Vaag, Allan; Groop, Leif; Maziarz, Marlena; Klovins, Janis; Ahlqvist, Emma; Ling, Charlotte.
Affiliation
  • García-Calzón S; Epigenetics and Diabetes Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Scania University Hospital, 214 28 Malmö, Sweden. sonia.garcia_calzon@med.lu.se charlotte.ling@med.lu.se.
  • Perfilyev A; Department of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.
  • Martinell M; Epigenetics and Diabetes Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Scania University Hospital, 214 28 Malmö, Sweden.
  • Ustinova M; Department of Public Health and Caring Sciences, Uppsala University, 751 22 Uppsala, Sweden.
  • Kalamajski S; Latvian Biomedical Research and Study Centre, Ratsupites Street 1, k-1, Riga LV-1067, Latvia.
  • Franks PW; Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University Diabetes Centre, 214 28 Malmö, Sweden.
  • Bacos K; Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University Diabetes Centre, 214 28 Malmö, Sweden.
  • Elbere I; Epigenetics and Diabetes Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Scania University Hospital, 214 28 Malmö, Sweden.
  • Pihlajamäki J; Latvian Biomedical Research and Study Centre, Ratsupites Street 1, k-1, Riga LV-1067, Latvia.
  • Volkov P; Institute of Public Health and Clinical Nutrition, Internal Medicine, University of Eastern Finland, 70211 Kuopio, Finland.
  • Vaag A; Clinical Nutrition and Obesity Center, Kuopio University Hospital, 70210 Kuopio, Finland.
  • Groop L; Epigenetics and Diabetes Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Scania University Hospital, 214 28 Malmö, Sweden.
  • Maziarz M; Type 2 Diabetes Biology Research, Steno Diabetes Center, 2820 Gentofte, Denmark.
  • Klovins J; Genomics, Diabetes and Endocrinology Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Scania University Hospital, 214 28 Malmö, Sweden.
  • Ahlqvist E; Bioinformatics Unit, Department of Clinical Sciences, Lund University Diabetes Centre, 214 28 Malmö, Sweden.
  • Ling C; Latvian Biomedical Research and Study Centre, Ratsupites Street 1, k-1, Riga LV-1067, Latvia.
Sci Transl Med ; 12(561)2020 09 16.
Article in En | MEDLINE | ID: mdl-32938793
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Diabetes Mellitus, Type 2 / Metformin Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2020 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Diabetes Mellitus, Type 2 / Metformin Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2020 Document type: Article Country of publication: United States