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Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations.
Aleo, Serena J; Del Dotto, Valentina; Fogazza, Mario; Maresca, Alessandra; Lodi, Tiziana; Goffrini, Paola; Ghelli, Anna; Rugolo, Michela; Carelli, Valerio; Baruffini, Enrico; Zanna, Claudia.
Affiliation
  • Aleo SJ; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, Bologna 40126, Italy.
  • Del Dotto V; Unit of Neurology, Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Bologna 40139, Italy.
  • Fogazza M; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, Bologna 40126, Italy.
  • Maresca A; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna 40139, Italy.
  • Lodi T; Department of Chemistry, Life Science and Environmental Sustainability, University of Parma, Parma 43124, Italy.
  • Goffrini P; Department of Chemistry, Life Science and Environmental Sustainability, University of Parma, Parma 43124, Italy.
  • Ghelli A; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, Bologna 40126, Italy.
  • Rugolo M; Department of Pharmacy and Biotechnology (FABIT), University of Bologna, Bologna 40126, Italy.
  • Carelli V; Unit of Neurology, Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Bologna 40139, Italy.
  • Baruffini E; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna 40139, Italy.
  • Zanna C; Department of Chemistry, Life Science and Environmental Sustainability, University of Parma, Parma 43124, Italy.
Hum Mol Genet ; 29(22): 3631-3645, 2021 01 21.
Article in En | MEDLINE | ID: mdl-33231680
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurodegenerative Diseases / Optic Atrophy, Autosomal Dominant / Drug Repositioning / GTP Phosphohydrolases Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2021 Document type: Article Affiliation country: Italy Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurodegenerative Diseases / Optic Atrophy, Autosomal Dominant / Drug Repositioning / GTP Phosphohydrolases Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2021 Document type: Article Affiliation country: Italy Country of publication: United kingdom