STAT3 enhances radiation-induced tumor migration, invasion and stem-like properties of bladder cancer.

Wang, Fang; Ma, Xiangli; Mao, Guangmin; Zhang, Xiangyan; Kong, Zhaolu

Wang, Fang; Ma, Xiangli; Mao, Guangmin; Zhang, Xiangyan; Kong, Zhaolu.

Affiliation

Wang F; Department of Radiobiology, Institute of Radiation Medicine, Fudan University, Shanghai 200032, P.R. China.
Ma X; Department of Radiobiology, Institute of Radiation Medicine, Fudan University, Shanghai 200032, P.R. China.
Mao G; Department of Radiobiology, Institute of Radiation Medicine, Fudan University, Shanghai 200032, P.R. China.
Zhang X; Department of Radiobiology, Institute of Radiation Medicine, Fudan University, Shanghai 200032, P.R. China.
Kong Z; Department of Radiobiology, Institute of Radiation Medicine, Fudan University, Shanghai 200032, P.R. China.

Mol Med Rep ; 23(1)2021 01.

Article in En | MEDLINE | ID: mdl-33236137

Subject(s)

Cell Movement/radiation effects; Neoplasm Proteins/metabolism; Neoplastic Stem Cells; Radiation Tolerance; STAT3 Transcription Factor/metabolism; Urinary Bladder Neoplasms; Animals; Cell Line, Tumor; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplastic Stem Cells/metabolism; Neoplastic Stem Cells/pathology; Urinary Bladder Neoplasms/metabolism; Urinary Bladder Neoplasms/pathology; Urinary Bladder Neoplasms/radiotherapy; Xenograft Model Antitumor Assays

Key words

signal transduction and transcription activator 3; radiosensitivity; cancer stem cell; bladder cancer

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation Tolerance / Neoplastic Stem Cells / Urinary Bladder Neoplasms / Cell Movement / STAT3 Transcription Factor / Neoplasm Proteins Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Mol Med Rep Year: 2021 Document type: Article

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