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Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study.
Choi, Na Rae; Lee, Jung Han; Park, Jin Young; Hwang, Dae Seok.
Affiliation
  • Choi NR; Department of Oral Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan 50612, Korea.
  • Lee JH; Department of Oral Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan 50612, Korea.
  • Park JY; Department of Oral Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan 50612, Korea.
  • Hwang DS; Department of Oral Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan 50612, Korea.
Int J Environ Res Public Health ; 17(23)2020 11 26.
Article in En | MEDLINE | ID: mdl-33256211
The purpose of this study was to confirm the success rate of surgical treatment of medication-related osteonecrosis of the jaw (MRONJ) in patients at a single institution (Association of Oral and Maxillofacial Surgery (AAOMS) stages 1, 2, or 3), and to identify the factors that influence treatment outcomes. As a result of analyzing the outcomes of treatment, surgical "success" was achieved in 93.97% (109) of cases, and "failure" was observed at 6.03% (7) cases. Analysis of patient factors that potentially affect treatment outcomes showed that zoledronate dose (p = 0.005) and the IV (intravenous) injection of drugs (p = 0.044) had significant negative impacts.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Bone Density Conservation Agents / Bisphosphonate-Associated Osteonecrosis of the Jaw Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Int J Environ Res Public Health Year: 2020 Document type: Article Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Bone Density Conservation Agents / Bisphosphonate-Associated Osteonecrosis of the Jaw Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Int J Environ Res Public Health Year: 2020 Document type: Article Country of publication: Switzerland